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Meningitis (from Greek μῆνιγξ méninx, "membrane" and the medical suffix -itis, "inflammation") is an acute inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges. The inflammation may be caused by infection with viruses, bacteria, or other microorganisms, and less commonly by certain drugs. Meningitis can be life-threatening because of the inflammation's proximity to the brain and spinal cord; therefore, the condition is classified as a medical emergency.
The most
common symptoms of meningitis are headache and neck
stiffness associated with fever, confusion or
altered consciousness, vomiting, and an inability to tolerate
light (photophobia)
or loud noises (phonophobia). Children often exhibit only nonspecific symptoms, such as irritability and
drowsiness. If a rash is
present, it may indicate a particular cause of meningitis; for instance, meningitis caused by meningococcal bacteria may
be accompanied by a characteristic rash.
A lumbar
puncture diagnoses or excludes meningitis. A needle is inserted into
the spinal canal to extract a sample of cerebrospinal fluid (CSF), that envelops
the brain and spinal cord. The CSF is examined in a medical laboratory. The
first treatment in acute meningitis consists of promptly administered antibiotics and
sometimes antiviral drugs. Corticosteroids can
also be used to prevent complications from excessive inflammation. Meningitis
can lead to serious long-term consequences such as deafness, epilepsy, hydrocephalus and cognitive
deficits, especially if not treated quickly. Some
forms of meningitis (such as those associated with meningococci, Haemophilus influenzae type B, pneumococci or mumps
virus infections) may be prevented by immunization. In
2013 meningitis resulted in 303,000 deaths – down from 464,000 deaths in 1990.
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