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Bronchitis is
inflammation of the bronchi (large and medium-sized airways) of the lungs. Symptoms
include coughing up mucus, wheezing, shortness of breath, and chest discomfort. Bronchitis
is divided into two types:acute and chronic. Acute
bronchitis is also known as a chest cold.
Acute
bronchitis usually has a cough that lasts around three weeks. In
more than 90% of cases the cause is aviral
infection. These
viruses may be spread through the air when people cough or by direct contact.
Risk factors include exposure to tobacco
smoke, dust, and other air
pollution. A
small number of cases are due to high levels of air pollution or bacteria such
as Mycoplasma pneumoniae or Bordetella pertussis. Treatment
of acute bronchitis typically involves rest, paracetamol (acetaminophen),
and NSAIDs to
help with the fever.
Chronic bronchitis is defined as a productive
cough that lasts for three months or more per year for at least two
years. Most
people with chronic bronchitis have chronic obstructive pulmonary
disease (COPD). Tobacco
smoking is the most common cause, with a number of other factors such
as air pollution and genetics playing
a smaller role. Treatments
include quitting smoking, vaccinations, rehabilitation, and often inhaled bronchodilators and steroids. Some
people may benefit from long-term
oxygen therapy or lung transplantation.
Acute
bronchitis is one of the most common diseases. About
5% of adults are affected and about 6% of children have at least one episode a
year. In
2010, COPD affects 329 million people or nearly 5% of the population. In
2013, it resulted in 2.9 million deaths up from 2.4 million deaths in 1990.
Acute
bronchitis, also known as a chest cold, is short term inflammation of
the bronchi of
the lungs. The
most common symptom is a cough. Other
symptoms include coughing up mucus,wheezing, shortness of breath, fever, and chest
discomfort. The infection may last from a few to ten days. The
cough may persist for several weeks afterwards with the total duration of
symptoms usually around three weeks. Some
have symptoms for up to six weeks.
In more than
90% of cases the cause is a viral
infection. These
viruses may be spread through the air when people cough or by direct contact.
Risk factors include exposure to tobacco
smoke, dust, and other air
pollution. A
small number of cases are due to high levels of air pollution or bacteria such
as Mycoplasma pneumoniae or Bordetella pertussis. Diagnosis
is typically based on a person's signs and symptoms. The
color of the sputum does not indicate if the infection is viral or bacterial.
Determining the underlying organism is typically not needed. Other
causes of similar symptoms include asthma, pneumonia, bronchiolitis, bronchiectasis,
and COPD. A chest X-ray may
be useful to detect pneumonia.
Prevention
is by not smoking and avoiding other lung irritants. Frequent hand washing may
also be protective. Treatment
of acute bronchitis typically involves rest, paracetamol (acetaminophen),
and NSAIDs to
help with the fever, Cough
medicine has little support for its use and is not recommended in
children less than six years of age. There
is tentative evidence that salbutamol may
be useful in those with wheezing; however, it may result in nervousness. Antibiotics should
generally not be used. An
exception is when acute bronchitis is due to pertussis.
Tentative evidence supports honey and pelargonium to
help with symptoms.
Chronic
bronchitis
Main
article: Chronic obstructive pulmonary
disease
Chronic bronchitis is defined as a productive
cough that lasts for three months or more per year for at least two
years. Most
people with chronic bronchitis have chronic obstructive pulmonary
disease(COPD). Protracted
bacterial bronchitis is defined as a chronic productive cough with a positive bronchoalveolar lavage that resolves
with antibiotics. Symptoms
of chronic bronchitis may include wheezing and shortness of breath, especially
upon exertion and low oxygen saturations. The
cough is often worse soon after awakening and the sputum produced may have a
yellow or green color and may be streaked with specks of blood.
Most cases
of chronic bronchitis are caused by smoking cigarettes or other forms of
tobacco. Additionally,
chronic inhalation of air pollution or irritating fumes or dust from hazardous
exposures in occupations such as coal mining, grain handling, textile
manufacturing, livestock farming, and
metal moulding may also be a risk factor for the development of chronic
bronchitis. Protracted
bacterial bronchitis is usually caused by Streptococcus pneumoniae, Non-typable Haemophilus influenzae, or Moraxella catarrhalis.
Individuals
with an obstructive pulmonary disorder such as bronchitis may present with a
decreased FEV1 and FEV1/FVC
ratio on pulmonary function tests. Unlike
other common obstructive disorders such as asthma or emphysema,
bronchitis rarely causes a high residual
volume (the volume of air remaining in the lungs after a maximal
exhalation effort).
Evidence
suggests that the decline in lung function observed in chronic bronchitis may
be slowed with smoking cessation. Chronic
bronchitis is treated symptomatically and may be treated in a nonpharmacologic
manner or with pharmacologic therapeutic agents. Typical nonpharmacologic
approaches to the management of COPD including bronchitis may include: pulmonary rehabilitation, lung volume reduction surgery, and lung transplantation. Inflammation
and edema of the respiratory epithelium may be reduced with inhaled corticosteroids. Wheezing
and shortness of breath can be treated by reducing bronchospasm (reversible
narrowing of smaller bronchi due to constriction of the smooth
muscle) with bronchodilators such as inhaled long acting β2-adrenergic
receptor agonists (e.g.,salmeterol)
and inhaled anticholinergics such as ipratropium
bromide or tiotropium bromide. Mucolytics may
have a small therapeutic effect on acute exacerbations of chronic bronchitis. Supplemental
oxygen is used to treat hypoxemia (too
little oxygen in the blood) and has been shown to reduce mortality in chronic
bronchitis patients. Oxygen
supplementation can result in decreased respiratory
drive, leading to increased blood levels of carbon
dioxide(hypercapnea) and subsequent respiratory acidosis.
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